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Staphylococcus aureus provides information on food borne outbreaks of disease and their impact on human health. It is for anyone interested in the features of the pathogen, and its food safety aspects, as well as its prevalence and possible control and eradication options. This is a practical reference for those in the food industry, but also includes some theoretical information useful for advising. The book introduces detailed features and molecular biology of the pathogen, as well as selective methods of detection, prevention and eradication essential for research. It covers methicillin-resistant staphylococcus aureus for food related industries, information on genetic lineages, cell wall components, cell division machinery, molecular characterization, and capillary electrophoresis for detecting and characterizing staphylococcus aureus. Includes information on established and novel antibiotic agents for experimental studies and methods of control and eradicationPresents use cases of outbreak studies in molecular and cell biologyProvides summary points of detection methods and applicability of those methods to other foodborne pathogensCovers the Staphylococcus aureus' mode of transmission, detection, biology and impact on foodborne illness
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Genetic Diseases of the Kidney provides expert insight into the role of genetic abnormalities in the pathogenesis of deranged kidney function and kidney disease. The principles of mammalian genetics are first elaborated, with special consideration given to the application of genetic analysis to clinical syndromes and diseases. Specific renal diseases are next analyzed. Monogenic disorders confined to the kidney - diseases of nephron function, renal development, and renal neoplasia - are then treated in detail in some 30 chapters. Both specific diseases - Fanconi syndrome, Bartter's
Kidneys --- Diseases --- Genetic aspects.
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"[This book] is aimed at students of bone biology and genetics and includes general introductory chapters on bone biology and genetics. More specific disease orientated chapters comprehensively summarize the clinical, genetic, molecular, animal model, molecular pathology, diagnostic, counseling, and treatment aspects of each disorder. The book is organized into five sections that each emphasize a particular theme, general background to bone biology, general background to genetics and epigenetics, disorders of bone and joint, parathyroid and related disorders, and vitamin D and renal disorders.The first section is specifically devoted to providing an overview of bone biology and structure, joint and cartilage biology, principles of endocrine regulation of bone, and the role of neuronal regulation and energy homeostasis. The second section reviews the principles and progress of medical genetics and epigenetics related to bone disease, including genome-wide association studies (GWAS), genomic profiling, copy number variation, prospects of gene therapy, pharmacogenomics, genetic testing and counseling, as well as the generation and utilizing of mouse models.The third section details advances in the genetics and molecular biology of bone and joint diseases, both monogenic and polygenic, as well as skeletal dysplasias, and rarer bone disorders. The fourth section highlights the central role of the parathyroids in calcium and skeletal homeostasis by reviewing the molecular genetics of: hyperparathyroidism, hypoparathyrodism, endocrine neoplasias, and disorders of the PTH and calcium-sensing receptors. The fifth section details molecular and cellular advances across associated renal disorders such as vitamin D and rickets." -- from website publisher
Mammals --- Bones --- Diseases --- Genetic aspects.
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Human genetics --- Oncology. Neoplasms --- Cancer --- Genetic aspects.
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Psychiatry --- Sociology of health --- Schizophrenia --- Genetic aspects.
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Non-coding RNA. --- Cancer --- Genetic aspects.
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Oncogenomics: From Basic Research to Precision Medicine offers a thorough survey of precision medicine and its diagnostic and therapeutic applications in oncology. Gathering contributions from leading international researchers in the field, chapters examine recent translational advances in oncogenomic methods and technologies, detail novel molecular classifications of tumors, and identify diagnostic and prognostic biomarkers for various types of cancers, including pancreatic, gastrointestinal, breast, hematological, lung, osteotropic, genitourinary, and skin cancers. This book provides a foundation for clinical oncologists, human geneticists, and physicians to develop new targeted cancer treatments and incorporate genomic medicine into clinical practice.
Genetics --- Cancer --- Genetic aspects. --- Molecular aspects.
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Pathological dermatology --- Human genetics --- Skin --- Diseases --- Genetic aspects --- Congresses --- Skin - Diseases - Genetic aspects - Congresses.
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Human genetics --- Abnormalities, Human --- Abnormalities --- Genetic aspects --- Congresses. --- congresses.
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Currently, intensive effort is being directed toward the identification of molecular targets that can provide approaches to the development of novel therapeutic strategies in cancer management. This book focuses on metastasis-associated genes, metastasis promoter and suppressor genes, which relate specifically to behavioral alterations of cancer cells in epithelial mesenchymal transition, cancer stem cell maintenance and propagation, and to the acquisition of invasive and metastasis faculty. The function of these genes has implications for cell cycle regulation and cell proliferation and so
Oncology. Neoplasms --- Cancer --- Molecular aspects. --- Genetic aspects. --- Treatment.
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